Pushing property limits in materials discovery via boundless objective-free exploration

Pushing the limits of crystallography

A very serious concern of scientists dealing with crystal structure refinement, including theoretical research, pertains to the characteristic bias in calculated versus measured diffraction intensities, observed particularly in the weak reflection regime. This bias is here attributed to corrective factors for phonons and, even more distinctly, phasons, and credible proof supporting this assumpt...

Pushing limits by embracing complexity.

In this essay, celebrating the tenth anniversary of this journal, the author describes his journey, from being an engineering student to being a researcher in the biomolecular and biomedical sciences. Along the way, he is going to explain how he learned that handling the complexity of biological systems and cellular processes can provide guidance in situation we all face in our everyday life. I...

Pushing the limits of SPM

Breaking the speed limit One of the serious, inherent limitations in all forms of SPM is the low imaging rate. This is because each image is built up pixel by pixel in a sequential scan of the surface. The scanning motion involves electronically controlled mechanical displacements, and usually some form of feedback is applied between a control parameter, such as tunneling current or force, and ...

Pushing the Limits in Sequential Sorting

With re nements to the WEAK-HEAPSORT algorithm we establish the general and practical relevant sequential sorting algorithm RELAXED-WEAK-HEAPSORT executing exactly ndlog ne 2 ne + 1 n log n 0:9n comparisons on any given input. The number of transpositions is bounded by n plus the number of comparisons. Experiments show that RELAXED-WEAK-HEAPSORT only requires O(n) extra bits. Even if this space...

Pushing the limits of detection and sensitivity in label-free interaction analysis